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Limonene is a wonderful aromatic found in the peels of citrus fruits like oranges, lemons, and limes (Hence its name). It provides a fruity-citrus taste and often lends itself to a delightfully sweet smell. Unfortunately, there is not a large body of research into the specific biological effects or methods of action; However, some small studies exist and when combining data gathered from the experiences of those who smoke strains high in limonene, we can form a clearer picture of what effects it offers.

Limonene is most often associated with elevated mood and stress relief so there is limited clinical evidence that limonene-heavy strains have more powerful anxiolytic (anxiety-reducing) properties.

Of Limonene’s most interesting medical benefits is its potential cancer-fighting capabilities. Limonene has been found to slow the growth of skin, breast, and mammary, tumors in both human and mouse models. Another study found that taking limonene supplements for 4-6 weeks helped stop the production of a protein called IGFBP-3, which in turn led to a reduction in breast tumor growth. Other labs have found benefits to limonene in Brain and Lung cancer models. It has also been found that limonene may help relieve the discomfort of heartburn and gastric reflux.

Limonene also seems to improve the absorption of other terpenes in delivery methods like topical lotions and balms as well as oral or sublingual administration routes. For this reason, it is ideal when making edibles or THC/CBD lotions.

Caryophyllene is a rather unique terpene because it is known to interact with the endo-cannabinoid system (ECS) and produce a powerful anti-inflammatory response that can manage pain. Caryophyllene is the only terpene known to exist that can also act as a cannabinoid and interact directly with the ECS by binding to the CB2 receptors in the central nervous system.

Caryophyllene is found in many herbs/spices throughout the world; including Basil, black pepper, and oregano. People who smoke cannabis strains with high levels of caryophyllene often report a spicy warmth in the nose and mouth. This flavor is frequently compared to that of cinnamon and cloves.

The Terpene α-Bisabolol is best known for its pleasant scent. It is most often described as having a sweet and floral profile which makes it ideal for strains that play on their earthy elements. α-Bisabolol is common in herbal teas and can be found naturally in chamomile. It is common in beauty and cosmetic products because it is associated with anti-inflammatory that can reduce the uterine pain experienced during pregnancy and potentially even the menstrual cycle.

As its name so obviously suggests, Pinene smells like a pine tree. Pine isn’t just found in pine trees, it's the most abundant terpene in nature and can also be found in conifer trees, orange peels, turpentine, rosemary, dill, basil, and parsley. In cannabis Pinene can provide powerful anti-inflammatory effects, soothing anti-anxiety effects, and mild pain relief, and α-Pinene may even help prevent the short term memory impairment commonly associated with a cannabis high.